Clinical Research Forum - 180208

"BRCA1 and Women’s Cancer: Moving the Needle towards Mechanism based Diagnostics and Therapy"

Presented by Dr. Veena N Rao, PhD.

 

Presentation

Breast cancer is the second leading cause of cancer-related deaths among women. Majority of young women with BRCA1 mutations have a so-called triple negative breast cancer (TNBC) and high grade serous ovarian cancer (HGSOC) with an aggressive phenotype. Currently there is no targeted therapy for TNBC and HGSOC. Work ongoing in the lab is geared towards understanding the molecular mechanism of BRCA1 dysfunction in these cancers. We are studying the biological functions of BRCA1 and its disease associated mutant proteins so as to identify the driver mutations that lead to these aggressive cancers. This work as led to the discovery of a BRCA1 function based assay Patent 8,372,580 the only one in the world that can stratify risk for TNBC and HGSOC development and can be used to develop drugs for targeted therapy of these cancers which currently have no targeted treatments available.

 

PMI Atlanta Toastmasters Meeting - 180208

Kroger Community Room, Kroger, Fountain Oaks Shopping Center

If you would like to earn PDUs while improving your communications and leadership skills, this opportunity is for you! PMI Atlanta has teamed up with Toastmasters International to offer you a chance to hone your public speaking, critical listening, and leadership skills in a supportive environment. You will also have an opportunity to practice speaking off-the-cuff, giving and receiving feedback, emceeing a meeting, and many other valuable business skills. Since this club is exclusively for PMI Atlanta members, you will also have an opportunity to develop bonds within the PMI community.